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Home>>Products>>fluticasone propionate CAS 80474-14-2 FACTORY SUPPLY C25H31F3O5S

fluticasone propionate CAS 80474-14-2 FACTORY SUPPLY C25H31F3O5S

CAS NO.80474-14-2

  • FOB Price: USD: 2.00-2.00 /Metric Ton Get Latest Price
  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,T/T,MoneyGram
  • Available Specifications:

    pharma grade(1-100)Metric Ton

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Product Details

Keywords

  • fluticasone propionate
  • 80474-14-2
  • FLIXONASE

Quick Details

  • ProName: fluticasone propionate CAS 80474-14-2 ...
  • CasNo: 80474-14-2
  • Molecular Formula: C25H31F3O5S
  • Appearance: Crystalline Solid
  • Application: An antiallergic and anti inflammatory
  • DeliveryTime: within 10 days once got your order
  • PackAge: In Aluminium Foil Packing,500G;1KG;5KG...
  • Port: Shanghai port,Qingdao port,Guangzhou p...
  • ProductionCapacity: 1000 Metric Ton/Year
  • Purity: 99%min
  • Storage: Room temperature, dark, sealed and pre...
  • Transportation: Cooperaing with our International frei...
  • LimitNum: 1 Kilogram
  • Moisture Content: less0.1
  • Impurity: less 0.2%

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Details

Density: 1.32 g/cm3
Melting Point: 275oC
Boiling Point: 568.3oC at 760 mmHg
Flash Point: 297.5oC
Refractive Index: 31 ° (C=1, Dioxane)
Storage Condition: Store in original container in a cool dark place.

Chemical Properties Crystalline Solid
Uses An antiallergic and anti inflammatory
Uses A derivative of Flumethasone. An antiallergic; anti-asthmatic; anti-inflammatory.
Uses antiviral
Uses Atorvastatin Intermediate
Uses A high-affinity, selective glucocorticoid receptor agonist
Definition ChEBI: A trifluorinated corticosteroid that consits of 6alpha,9-difluoro-11beta,17alpha-dihydroxy-17beta-{[(fluoromethyl)sulfanyl]carbonyl}-16-methyl-3-oxoandrosta-1,4-diene bearing a propionyl s bstituent at position 17; has anti-inflammatory, anti-asthmatic and anti-allergic activity.
Brand name Cutivate (Altana); Flonase (GlaxoSmithKline); Flovent (GlaxoSmithKline).
Biological Activity High affinity, selective glucocorticoid receptor agonist (K d = 0.5 nM). Potently stimulates glucocorticoid receptor-mediated transactivation of gene expression and enhances human eosinophil apoptosis (EC 50 = 3.7 nM) in vitro . Inhibits mast cell accumulation in nasal mucosa following topical administration. Lipophilic, clinically-used anti-inflammatory agent with low oral bioavailability.

 

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